PubMed Architect

Biomedical Evidence Operating System

Search less.
Synthesize with traceability.

A local-first research workspace that connects PubMed discovery, source-bound AI appraisal, evidence matrices, living reviews, and manuscript drafting.

Reproducibility ledger

Recent evidence activity

NCBI literature workspace

From search question
to structured evidence.

Search PubMed by topic, PMID, or DOI. Review abstracts, save sources, and build a manuscript without leaving your browser.

Structured comparison

Evidence Matrix

A transparent screening layer derived from PubMed metadata and abstract reporting—not a substitute for a validated risk-of-bias instrument.

Your evidence matrix is empty

Add PubMed records to the library; they will appear here automatically.

SelectStudyDesignReportingScreening gradeSource

Metadata network

Evidence Knowledge Graph

Article MeSH / keyword

Connections are generated locally from shared MeSH terms in your saved records. They represent co-indexing, not biological causality.

Your evidence base

Citation Library

No saved sources yet

Search PubMed and add articles to build your working library.

Structured drafting

Article Builder

Saved locally
0 words

Grounded writing

AI Citation Writer

Generate manuscript-ready sentences supported only by selected PubMed records.

Select evidence 0 selected

Save citations to your library first.

The AI receives the selected abstracts and optional draft context. Verify every generated claim against the original article before use.

Versioned synthesis

Living Review Builder

Capture a reproducible review snapshot that can be refreshed when new PubMed records are found.

Saved locally

Protocol

About the project

Research tools, without the clutter.

01

Live PubMed search

Queries NCBI E-utilities directly. Search by keywords, PMID, or DOI and inspect complete abstracts.

02

Private by design

Your library and article draft remain in this browser's local storage. No account or server is involved.

03

Open workflow

Export citations and manuscripts in portable formats, then continue in your preferred research environment.

PubMed Architect is a research aid, not a substitute for critical appraisal or clinical judgment. PubMed data are provided by the U.S. National Library of Medicine.

Direct provider connection

AI research settings

Keys are held only in this browser tab's session storage and sent directly to the provider you select. They are never committed to GitHub or included in exports.

OpenAINot configured
AnthropicNot configured
NCBIStandard access

Added to NCBI requests only. The API key remains in this tab session.

Important: browser-entered keys are visible to JavaScript running on this page. Use restricted project keys with spending limits and clear them when finished. Do not paste patient-identifiable information into prompts.